KARTEPE MANUFACTURING SITE
DEVA Holding Kartepe Manufacturing Facilities, located on İzmit - Ankara highway, in Kocaeli Kartepe district, founded on an area of 32,000 m2, with a closed area of 16,500 m2, comprise of state-of-the-art buildings where sterile liquid drugs, empty medical ampoules, and colognes are manufactured.

Sterile Liquid Drug Manufacturing Unit

Sterile liquid ampoules for injection, sterile liquid vials for injection, sterile liquid lyophilized vials for injection, and sterile liquid eye drops in PE bottles, sterile liquid diluent vials and vials containing sterile inhalation powder for nebulization by BFS (blow-fill-seal) technology can be manufactured in Kartepe sterile liquid drug manufacturing facilities.

In our facilities, in which 42.3 million units of sterile liquid drugs were manufactured in 2019, a total of 46.9 million units were produced in 2020. Compared to 2019, an increase in production of approximately 11% was achieved.

 

Manufacture of Sterile Ampoules for Injection

In our facility, in which a total of 26.22 million units of ampoules and 32.87 million solvent ampoules were manufactured in 2019, a total of 32.49 million units of ampoules and 36.33 million solvents were produced in 2020. The total number of single ampoules we manufactured in 2020 is 141 million.

 

Manufacture of Sterile Liquid Vials for Injection and Sterile Liquid Lyophilized Vials for Injection

On our production line for sterile liquid vials for injection and sterile liquid lyophilized vials for injection, on which a total of 11.2 million units of vials were manufactured in 2019, 11.11 million units of vials were manufactured in 2020.

BFS-SVP Manufacture

On the BFS-SVP production line on which a total of 4.05 million units were produced in 2019, a total of approximately 3.3 million units of production was achieved in 2020.

 

Furthermore, in our facility, which was approved by the Ministry of Health, Ministry of Food, Agriculture and Livestock, and German Ministry of Health (for BFS-SVP production line), US FDA (by the United States Food and Drug Administration only for a sterile liquid vial and sterile liquid lyophilized vial production line) and Kenyan, Southern African, New Zealander (Medsafe), Portuguese (Infarmed) and Russian Health Authorities, inspections were carried out by the Ministry of Agriculture and Forestry, Infarmed (Portugal), Medsafe (New Zealand) and the Russian Health authorities and the notified body due to CE product certification by KIWA in 2019, and our facility successfully passed these inspections.



Sterile PE Bottle Production

In the newly established filling line for eye drops in PE bottles supplied ready-to-use, 27.000 units of preservativefree (PF) sterile eye drops were produced in 2020.

 

In addition, inspections were carried out mostly remotely particularly due to the pandemic in 2020 in our production lines and facilities approved by the Ministry of Health, the Ministry of Agriculture and Forestry, the German Ministry of Health (for our BFS-SVP production lines), the US FDA (by the Food and Drug Administration of the United States; some products produced only in sterile liquid vial and sterile liquid lyophilized vial production line) and by the health authorities of Kenya, South Africa, New Zealand (Medsafe), Portugal (Infarmed), Russia, United Arab Emirates, Philippines, Qatar, Iraq, Ivory Coast, Cambodia and Yemen, and the inspections by the Ministry of Health and the US FDA health authorities and the notified body KIWA and TUV Thuringen were successfully concluded



Manufacture of Empty Medical Ampoules

Our empty medical ampoule manufacturing unit meets a substantial part of the market’s need as one of the three leading medical ampoule manufacturing companies in our country.

Our facilities, which hold ISO 9001:2008 certificate, is audited by Thuringen on a periodical basis.

The number of empty ampoules we manufactured was 150.3 million in 2019 and 166.8 million in 2020.

Manufacture of Cologne

Boğaziçi Kolonyaları, one of Turkey’s best-selling brand, is produced in line with the Turkish Ministry of Health, Cosmetic GMP practices.

Our department, which holds the ISO 9001: 2015 certificate, is also periodically audited by TUV Thuringen.

While only 80° Lemon and Lavender cologne were produced in our department until 2020, where products appealing to various segments were produced, the newly developed perfumed cologne series started to be offered to the market in early 2020 with new bottle and spray forms in addition to the existing classic cologne types. Especially after March 2020, there has been an increase in production demands due to the pandemic. Also due to the pandemic, the spray lemon cologne product in a new 100 ml plastic bottle was launched in order to meet consumer demand. Our production numbers for colognes was 2.1 million in 2019 and 9.3 million in 2020. In Kartepe manufacturing facility, rate of capacity utilization was 88%. .

Production Indicators

The total human and veterinary products manufactured in our manufacturing facilities on a unit basis was 184.7 million units in 2017, 196.7 million units in 2018, 200.7 million units in 2019 and 205.8 million units in 2020.

The total manufacturing value (drugs and other) was realized as 401.1 million TL in 2017, 541.4 million TL in 2018, 687.6 million TL in 2019 and 868.8 million in 2020.